S-LDXR

S-LDXR is a software for estimating enrichment of stratified squared trans-ethnic genetic correlation across genomic annotations from GWAS summary statistics data. The latest version is version 0.3-beta.

Software requirement

The software was developed and tested with the following packages.

• Python 2.7.12
• NumPy 1.15.1
• Pandas 0.23.4
• PySnpTools 0.3
• SciPy 1.1.0
• StatsModels 0.9.0

Reference panels, annotations, LD scores, and demo

1000 Genomes Project reference panels, demo code and data for running S-LDXR, annotation files and LD score files for the baseline-LD-X model annotations, and several other annotations can be downloaded here.

Contact

• Huwenbo Shi: hshi_AT_hsph.harvard.edu
• Alkes Price: aprice_AT_hsph.harvard.edu